Laboratory Manager
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Laboratory Manager

King of Prussia, PA

The Center for Breakthrough Medicines is on track to be the largest single-site cell and gene therapy contract development and manufacturing organization in the world. Our comprehensive service offering accelerates speed to market through supply chain disruption mitigation strategies, end-to-end program management expertise and unique platform technology with the ability to follow a molecule from idea to commercialization. CBM’s integrated approach provides high quality and consistent end-to-end manufacturing capability including: Process and Analytical Development; Plasmid DNA production; Viral Vector Production of Lentivirus; AAV and Adenovirus; Testing and Analytics; Autologous, Allogeneic and Gene-edited Cell Therapy Bioprocessing; and Cell banking. CBM’s horizontal and vertical integration provides one source throughout a product’s life cycle.

CBM’s mission is to accelerate the delivery and affordability of lifesaving and life-changing therapies from discovery to market by offering a complete solution for the development and commercialization of cell and gene therapies.

CBM is located just outside of Philadelphia in the Heart of Cellicon Valley on The Discovery Labs campus set on 300 acres with 2.4 million square feet of life sciences lab and manufacturing space, allowing clients to scale their development and manufacturing needs without ever having to change sites, while providing employees a true community campus experience focused exclusively on life sciences.

The Discovery Labs is a Global Platform Company inclusive of CBM, The Discovery Labs Properties, UniteIQ incubator labs, and The Colony, a unique investment and resource model enabling groundbreaking therapies to be brought to life.


The Discovery Labs Center for Breakthrough Medicines is looking for a skilled Laboratory Manager to ensure operational efficiency and safety in the day-to-day operations of the department. The focus will be on facilitating a well-organized and highly functional Process Development (PD) laboratory work environment with an emphasis on inventory and equipment maintenance as well as enforcing existing and developing new laboratory policies relating to environmental, health, and safety. In this role, you will serve as a liaison to coordinate the varying support needs among the collaborative and cross-functional teams within and external to the PD department. Overall, prior experience in Laboratory Management and familiarity with SAP driven processes will help to empower the operations of Process Development and continue the Center for Breakthrough Medicines’ success.


  • Responsible for establishing and maintaining the PD laboratory inventory system
  • Serves as a super-user for SAP ordering and inventory management system
  • Manages and coordinates equipment purchases, service agreements, calibrations, maintenance, and repairs
  • Trains staff on correct use of laboratory equipment and proper lab etiquette; drafts SOPs pertinent to the use of laboratory equipment and operations
  • Implement lean six sigma methodology (5S, Kanban, etc.) to ensure a highly functioning organization
  • Operates and responsible for autoclave, parts washer, and other general laboratory equipment
  • Organizes the laboratory schedule
  • Communicates effectively with cross-functional teams to support PD operations
  • Works with Biosafety Officer to facilitate staff adherence to safety policies
  • Works diplomatically with laboratory staff to adhere to laboratory policies, operations, safety, and identifies areas of improvement in the PD laboratory
  • Provides timely feedback to management regarding laboratory issues and works with laboratory staff to promptly resolve lab-related matters


  • Bachelor’s Degree in Biology, Biotechnology, Molecular Biology, Engineering and/or related studies, or equivalent combination of education and experience
  • Preferred 2-5+ years of laboratory management experience within a fast-paced cell and molecular biology BSL-2 (or higher), Process Development, or Manufacturing laboratory environment
  • Knowledgeable of basic laboratory equipment operation, repair, maintenance, and ability to troubleshoot malfunctioning laboratory instruments
  • Prior hands-on experience in standard aseptic cell culture technique, molecular and immunoassays, bioreactor operation, or purification technologies is a plus
  • Strong ability to execute job duties with minimal supervision and works collaboratively with laboratory staff to implement solutions to improve laboratory operations
  • Excellent communication and organizational skills with the ability to multitask
  • Adept in operating computers and using Microsoft Office (Word, Excel, and PowerPoint)
  • Experience using SAP ordering/inventory management software is a plus

Compensation: TBD

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