The Center for Breakthrough Medicines is on track to be the largest single-site cell and gene therapy contract development and manufacturing organization in the world. Our comprehensive service offering accelerates speed to market through supply chain disruption mitigation strategies, end-to-end program management expertise and unique platform technology with the ability to follow a molecule from idea to commercialization. CBM’s integrated approach provides high quality and consistent end-to-end manufacturing capability including: Process and Analytical Development; Plasmid DNA production; Viral Vector Production of Lentivirus; AAV and Adenovirus; Testing and Analytics; Autologous, Allogeneic and Gene-edited Cell Therapy Bioprocessing; and Cell banking. CBM’s horizontal and vertical integration provides one source throughout a product’s life cycle.
CBM’s mission is to accelerate the delivery and affordability of lifesaving and life-changing therapies from discovery to market by offering a complete solution for the development and commercialization of cell and gene therapies.
CBM is located just outside of Philadelphia in the Heart of Cellicon Valley on The Discovery Labs campus set on 300 acres with 2.4 million square feet of life sciences lab and manufacturing space, allowing clients to scale their development and manufacturing needs without ever having to change sites, while providing employees a true community campus experience focused exclusively on life sciences.
The Discovery Labs is a Global Platform Company inclusive of CBM, The Discovery Labs Properties, UniteIQ incubator labs, and The Colony, a unique investment and resource model enabling groundbreaking therapies to be brought to life.
We seek an experienced Manufacturing leader to bring the Center for Breakthrough Medicine’s current Good Manufacturing Practices (cGMP) Cell Therapy manufacturing facility online, build the manufacturing team and manage and supervise the production activities. The Senior Director of Cell Therapy Manufacturing will be responsible for the overall operational management of the Cell Therapy Manufacturing Facility, including supervising manufacturing supervisors and operators specific to gene-mediated and non-gene mediated autologous or allogeneic cell-based therapies, or human cells, human tissues, and cellular and tissue-based products (HCT/Ps), The candidate will oversee all day-to-day GMP operations, including project and timeline management, budget, personnel, P&L, facility management, and coordination with the Quality Control and Quality Assurance functions. They will be responsible for ensuring the Cell Therapy Manufacturing delivers all services in a timely, compliant manner, while staying within budget. The Senior Director of Cell Therapy Manufacturing will be a key leader in the organization and will have client-facing interaction with innovator company subject matter experts and senior management. The position will develop operational cadence and staffing structures permitting supervision of shifts that cover 24/7 cell therapy operations and the establishment of appropriate training and retention programs for manufacturing associates and supervisors.
Reports to: Chief Operating Officer